The Impact of Stress on the Nervous System
Allostasis is the term for adaptive changes the body makes in response to changes in our environment, particularly psychological distress, illness, and injury.
Allostatic processes, such as the secretion of cortisol and increased heart rate and blood pressure, protect us and allow our body to maintain homeostasis.
But when allostatic processes are overused or used inefficiently, physiological dysregulation may occur. Allostatic load is a measure of this dysregulation and is described by Carbone (2021, p. 394) as “the cumulative, biological wear and tear due from long-term exposure to stress.”
The fight-or-flight response
Stressors can be emotional or physical, but the stress response is the same. When we experience a stressor, it activates stress hormones that produce physiological changes in the sympathetic nervous system.
The fight-or-flight response is an acute stress response. It prepares our body for a physical response to fight or to avoid the stressor. It is a protective mechanism designed to dissipate as danger passes. When the stress response continues without relief, it is no longer adaptive and can lead to chronic health conditions across the lifespan.
Chronic stress
Chronic stress, also called toxic stress, is prolonged or frequent activation and dysregulation of the stress response. Chronic stress is not adaptive. It is associated with cardiovascular disease, insulin resistance, cognitive decline, and mental health disorders including bipolar disorder, major depressive disorder, and anhedonia (Carbone, 2021).
Toxic stress is one mechanism by which childhood trauma and disadvantages such as poverty get “under the skin” and stay there to influence physical and mental health in adulthood (Evans, 2016). There is evidence that stress induced by adverse childhood experiences involves epigenetic modifications that turn our genes on and off without changing the DNA (Jiang et al., 2019).
Strategies for managing stress
The concept of allostatic load has significant implications for treatment and preventive care of mental health and wellbeing. Within this framework, the mind and body are understood as an integrated system.
In a conceptual review of the relationship between allostatic load and stress, McEwen (2005, p. 317) writes:
“The “mind” includes not only what goes on in the brain but also the visceral sensations, including pain, as well as inflammatory states and many other processes that take place throughout the body. These components influence mood, attention and arousal and have effects on cognitive function.”
Interventions such as mindfulness and deep breathing manipulate mind–body interactions and may lead to improvement in sympathetic function. The ability to regulate our nervous system with self-directed, real-time, deliberate techniques is a powerful tool to improve the efficiency of our body to respond to stressors in everyday life.
Supplements and Diet
Diet and stress are bidirectionally related. Changes in mood because of stress can affect how much we eat. Overeating or not eating enough can increase stress-related mental health symptoms.
Diets high in fat are related to mood disorders. A Mediterranean diet with a high intake of vegetables, whole grains, and healthy oil may reduce the risk of depression (Bremner et al., 2020).
Often when we feel stressed, we experience gastrointestinal symptoms. Our gut communicates with our brain through our vagus nerve. These messages can be affected by the bacteria in the gut, called the gut microbiome. A healthy gut microbiome is related to positive mental health.
Eating foods high in whole grains, lean meats, and vegetables contributes to a healthy gut microbiome. Pre- and probiotic supplements can also improve gut health.
Check out this handout from Mental Health America that describes the gut–brain connection and the gut microbiome.
For tools to improve your gut microbiome health, read this article from the Huberman Lab.
What our readers think
The link to the nervous system video is broken.
Hi Kathy,
Thank you for informing us, and it was such an interesting video.
Since it is no longer available, it has been removed from the article.